{"id":3962,"date":"2026-01-26T10:17:53","date_gmt":"2026-01-26T10:17:53","guid":{"rendered":"https:\/\/www.sus-mirri.it\/2026\/01\/polyphenols-bioactive-metabolites-and-their-anti-biofilm-and-neuroprotective-potential\/"},"modified":"2026-01-26T10:55:54","modified_gmt":"2026-01-26T10:55:54","slug":"polyphenols-bioactive-metabolites-and-their-anti-biofilm-and-neuroprotective-potential","status":"publish","type":"post","link":"https:\/\/www.sus-mirri.it\/it\/2026\/01\/polyphenols-bioactive-metabolites-and-their-anti-biofilm-and-neuroprotective-potential\/","title":{"rendered":"Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential"},"content":{"rendered":"\n<p>Nazzaro, F., Coppola, F., Fratianni, F., Abdalrazeq, M., Ombra, M. N., De Giulio, B., Coppola, R., &amp; Zengin, G. 2025 Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential Foods 14(22) 3976\u00a0<a href=\"https:\/\/doi.org\/10.3390\/foods14223976\">https:\/\/doi.org\/10.3390\/foods14223976<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"html-abstract-title\">Abstract<\/h2>\n\n\n\n<p>Polyphenols are widely studied phytochemicals with well-known antioxidant and anti-inflammatory properties. They are commonly present in fruits, vegetables, and plant-based foods. Beyond these classical roles, growing evidence shows that polyphenol-derived bioactive metabolites\u2014produced or modified by the gut microbiota\u2014can promote host health. These metabolites are increasingly recognized for shaping host\u2013microbe interactions and influencing neurophysiological functions via the gut\u2013brain axis. This review provides an overview of polyphenol transformation rates by the gut microbiome, highlighting their microbial transformation, anti-biofilm effects, and neuroprotective potential. In our opinion, a deeper understanding of the properties of these metabolites can significantly impact food science and biotechnology.<\/p>\n\n\n\n<p>Read more at: <a href=\"https:\/\/www.mdpi.com\/2304-8158\/14\/22\/3976\">https:\/\/www.mdpi.com\/2304-8158\/14\/22\/3976<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nazzaro, F., Coppola, F., Fratianni, F., Abdalrazeq, M., Ombra, M. N., De Giulio, B., Coppola, R., &amp; Zengin, G. 2025 Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential Foods 14(22) 3976\u00a0https:\/\/doi.org\/10.3390\/foods14223976 Abstract Polyphenols are widely studied phytochemicals with well-known antioxidant and anti-inflammatory properties. They are commonly present in fruits, vegetables, and plant-based foods. Beyond [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":3960,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[58],"tags":[108,64],"class_list":["post-3962","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-it","tag-pubblications-it","tag-sus-mirri-it"],"uagb_featured_image_src":{"full":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4.png",1080,1080,false],"thumbnail":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-150x150.png",150,150,true],"medium":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-300x300.png",300,300,true],"medium_large":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-768x768.png",768,768,true],"large":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-1024x1024.png",1024,1024,true],"1536x1536":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4.png",1080,1080,false],"2048x2048":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4.png",1080,1080,false],"blade-grve-large-rect-horizontal":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-1080x658.png",1080,658,true],"blade-grve-small-square":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-600x600.png",600,600,true],"blade-grve-small-rect-horizontal":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-800x600.png",800,600,true],"blade-grve-small-rect-horizontal-wide":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-800x450.png",800,450,true],"blade-grve-small-rect-vertical":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-600x800.png",600,800,true],"blade-grve-medium-rect-vertical":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4-560x1080.png",560,1080,true],"blade-grve-medium-square":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4.png",1080,1080,false],"blade-grve-fullscreen":["https:\/\/www.sus-mirri.it\/wp-content\/uploads\/2026\/01\/SUS-MIRRI-4.png",1080,1080,false]},"uagb_author_info":{"display_name":"Maria Gullo","author_link":"https:\/\/www.sus-mirri.it\/it\/author\/maria-gullo\/"},"uagb_comment_info":0,"uagb_excerpt":"Nazzaro, F., Coppola, F., Fratianni, F., Abdalrazeq, M., Ombra, M. N., De Giulio, B., Coppola, R., &amp; Zengin, G. 2025 Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential Foods 14(22) 3976\u00a0https:\/\/doi.org\/10.3390\/foods14223976 Abstract Polyphenols are widely studied phytochemicals with well-known antioxidant and anti-inflammatory properties. They are commonly present in fruits, vegetables, and plant-based foods. Beyond&hellip;","_links":{"self":[{"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/posts\/3962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/comments?post=3962"}],"version-history":[{"count":1,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/posts\/3962\/revisions"}],"predecessor-version":[{"id":3963,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/posts\/3962\/revisions\/3963"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/media\/3960"}],"wp:attachment":[{"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/media?parent=3962"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/categories?post=3962"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sus-mirri.it\/it\/wp-json\/wp\/v2\/tags?post=3962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}